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Research

Heart


Conventional MRI provides ejection fraction which is currently an important marker for diagnosing many diseases. However, it may not provide a complete picture of cardiac mechanics. Therefore, non-invasive estimate of myocardial stiffness might provide important information regarding mechanical function of the heart. Cardiac MRE has a potential to diagnose a variety of cardiac disease states such as heart failure with preserved ejection fraction (HFPEF), hypertrophic cardiomyopathy (HCM), load independent contractility, myocardial infarction(MI) etc, where stiffness can be an important marker. An example of Cardiac MRE performed in a HCM patient is shown below.

Myocardial MRE: Normal (Loop)

 
  Dynamic Stiffness Map (kPa)

 

 

Cardiac MRE

   
 

Normal Volunteer

   
Magnitude Wave Image Stiffness Map  

Hypertrophic Cardiomyopathy